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Solution structure and biophysical characterization of the multifaceted signalling effector protein growth arrest specific-1

BACKGROUND: The protein growth arrest specific-1 (GAS1) was discovered based on its ability to stop the cell cycle. During development it is involved in embryonic patterning, inhibits cell proliferation and mediates cell death, and has therefore been considered as a tumor suppressor. GAS1 is known t...

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Detalles Bibliográficos
Autores principales: Rosti, Katja, Goldman, Adrian, Kajander, Tommi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349606/
https://www.ncbi.nlm.nih.gov/pubmed/25888394
http://dx.doi.org/10.1186/s12858-015-0037-6