Leishmania infantum Modulates Host Macrophage Mitochondrial Metabolism by Hijacking the SIRT1-AMPK Axis

Metabolic manipulation of host cells by intracellular pathogens is currently recognized to play an important role in the pathology of infection. Nevertheless, little information is available regarding mitochondrial energy metabolism in Leishmania infected macrophages. Here, we demonstrate that durin...

Descripción completa

Detalles Bibliográficos
Autores principales: Moreira, Diana, Rodrigues, Vasco, Abengozar, Maria, Rivas, Luis, Rial, Eduardo, Laforge, Mireille, Li, Xiaoling, Foretz, Marc, Viollet, Benoit, Estaquier, Jérôme, Cordeiro da Silva, Anabela, Silvestre, Ricardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349736/
https://www.ncbi.nlm.nih.gov/pubmed/25738568
http://dx.doi.org/10.1371/journal.ppat.1004684

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349736/
https://www.ncbi.nlm.nih.gov/pubmed/25738568
http://dx.doi.org/10.1371/journal.ppat.1004684

Ejemplares similares