Inhibition of Methyltransferases Accelerates Degradation of cFLIP and Sensitizes B-Cell Lymphoma Cells to TRAIL-Induced Apoptosis

Non-Hodgkin lymphomas (NHLs) are characterized by specific abnormalities that alter cell cycle regulation, DNA damage response, and apoptotic signaling. It is believed that cancer cells are particularly sensitive to cell death induced by tumor necrosis factor α–related apoptosis-inducing ligand (TRA...

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Detalles Bibliográficos
Autores principales: Braun, Frank K., Mathur, Rohit, Sehgal, Lalit, Wilkie-Grantham, Rachel, Chandra, Joya, Berkova, Zuzana, Samaniego, Felipe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349737/
https://www.ncbi.nlm.nih.gov/pubmed/25738497
http://dx.doi.org/10.1371/journal.pone.0117994

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349737/
https://www.ncbi.nlm.nih.gov/pubmed/25738497
http://dx.doi.org/10.1371/journal.pone.0117994

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