Innovative Delivery of siRNA to Solid Tumors by Super Carbonate Apatite

RNA interference (RNAi) technology is currently being tested in clinical trials for a limited number of diseases. However, systemic delivery of small interfering RNA (siRNA) to solid tumors has not yet been achieved in clinics. Here, we introduce an in vivo pH-sensitive delivery system for siRNA usi...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xin, Yamamoto, Hirofumi, Nakanishi, Hiroyuki, Yamamoto, Yuki, Inoue, Akira, Tei, Mitsuyoshi, Hirose, Hajime, Uemura, Mamoru, Nishimura, Junichi, Hata, Taishi, Takemasa, Ichiro, Mizushima, Tsunekazu, Hossain, Sharif, Akaike, Toshihiro, Matsuura, Nariaki, Doki, Yuichiro, Mori, Masaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349808/
https://www.ncbi.nlm.nih.gov/pubmed/25738937
http://dx.doi.org/10.1371/journal.pone.0116022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349808/
https://www.ncbi.nlm.nih.gov/pubmed/25738937
http://dx.doi.org/10.1371/journal.pone.0116022

Ejemplares similares