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Astragaloside IV Protects against Isoproterenol-Induced Cardiac Hypertrophy by Regulating NF-κB/PGC-1α Signaling Mediated Energy Biosynthesis

We previously reported that Astragaloside IV (ASIV), a major active constituent of Astragalus membranaceus (Fisch) Bge protects against cardiac hypertrophy in rats induced by isoproterenol (Iso), however the mechanism underlying the protection remains unknown. Dysfunction of cardiac energy biosynthe...

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Detalles Bibliográficos
Autores principales: Zhang, Suping, Tang, Futian, Yang, Yuhong, Lu, Meili, Luan, Aina, Zhang, Jing, Yang, Juan, Wang, Hongxin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349820/
https://www.ncbi.nlm.nih.gov/pubmed/25738576
http://dx.doi.org/10.1371/journal.pone.0118759