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Identifying Prognostic Features by Bottom-Up Approach and Correlating to Drug Repositioning

BACKGROUND: Traditionally top-down method was used to identify prognostic features in cancer research. That is to say, differentially expressed genes usually in cancer versus normal were identified to see if they possess survival prediction power. The problem is that prognostic features identified f...

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Detalles Bibliográficos
Autores principales: Li, Wei, Yu, Jian, Lian, Baofeng, Sun, Han, Li, Jing, Zhang, Menghuan, Li, Ling, Li, Yixue, Liu, Qian, Xie, Lu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349868/
https://www.ncbi.nlm.nih.gov/pubmed/25738841
http://dx.doi.org/10.1371/journal.pone.0118672