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The Effect of Tumor Microenvironment on Autophagy and Sensitivity to Targeted Therapy in EGFR-Mutated Lung Adenocarcinoma

Lung cancer is the top cancer killer worldwide. Tyrosine kinase inhibitors (TKIs), for example erlotinib, are commonly used to target epidermal growth factor receptor (EGFR)-mutated lung adenocarcinoma (ADC). Autophagy is a cellular response to stress, serving as a protective mechanism during antica...

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Detalles Bibliográficos
Autores principales: Li, Yuan-Yuan, Lam, Sze-Kwan, Zheng, Chun-Yan, Ho, James Chung-Man
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349879/
https://www.ncbi.nlm.nih.gov/pubmed/25767609
http://dx.doi.org/10.7150/jca.11187