Diminished Reovirus Capsid Stability Alters Disease Pathogenesis and Littermate Transmission

Reovirus is a nonenveloped mammalian virus that provides a useful model system for studies of viral infections in the young. Following internalization into host cells, the outermost capsid of reovirus virions is removed by endosomal cathepsin proteases. Determinants of capsid disassembly kinetics re...

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Detalles Bibliográficos
Autores principales: Doyle, Joshua D., Stencel-Baerenwald, Jennifer E., Copeland, Courtney A., Rhoads, Jillian P., Brown, Judy J., Boyd, Kelli L., Atkinson, James B., Dermody, Terence S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349883/
https://www.ncbi.nlm.nih.gov/pubmed/25738608
http://dx.doi.org/10.1371/journal.ppat.1004693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4349883/
https://www.ncbi.nlm.nih.gov/pubmed/25738608
http://dx.doi.org/10.1371/journal.ppat.1004693

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