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AKT and 14-3-3 Regulate Notch4 Nuclear Localization

Members of the Notch family of transmembrane receptors, Notch1-4 in mammals, are involved in the regulation of cell fate decisions and cell proliferation in various organisms. The Notch4 isoform, which is specific to mammals, was originally identified as a viral oncogene in mice, Int3, able to initi...

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Detalles Bibliográficos
Autores principales: Ramakrishnan, Gopalakrishnan, Davaakhuu, Gantulga, Chung, Wen Cheng, Zhu, He, Rana, Ajay, Filipovic, Aleksandra, Green, Andrew R., Atfi, Azeddine, Pannuti, Antonio, Miele, Lucio, Tzivion, Guri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350099/
https://www.ncbi.nlm.nih.gov/pubmed/25740432
http://dx.doi.org/10.1038/srep08782