DEPTOR has growth suppression activity against pancreatic cancer cells

DEPTOR was reported as a naturally occurring inhibitor of mTORC1 and mTORC2. The role of DEPTOR in the growth and survival of pancreatic cancer cells has not previously been determined. Here we report that while DEPTOR shows a cytoplasmic expression in both normal pancreatic acinar and islet cells i...

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Detalles Bibliográficos
Autores principales: Li, Hua, Sun, Grace Y., Zhao, Yongchao, Thomas, Dafydd, Greenson, Joel K., Zalupski, Mark M., Ben-Josef, Edgar, Sun, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350351/
https://www.ncbi.nlm.nih.gov/pubmed/25544749

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350351/
https://www.ncbi.nlm.nih.gov/pubmed/25544749

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