MYC regulates the non-coding transcriptome

Using RNA-seq (RNA sequencing) of ribosome-depleted RNA, we have identified 1,273 lncRNAs (long non-coding RNAs) in P493-6 human B-cells. Of these, 534 are either up- or downregulated in response to MYC overexpression. An increase in MYC occupancy near their TSS (transcription start sites) was obser...

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Detalles Bibliográficos
Autores principales: Hart, Jonathan R., Roberts, Thomas C., Weinberg, Marc S., Morris, Kevin V., Vogt, Peter K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2014
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350361/
https://www.ncbi.nlm.nih.gov/pubmed/25587025

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350361/
https://www.ncbi.nlm.nih.gov/pubmed/25587025

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