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Mannan adjuvants intranasally administered inactivated influenza virus in mice rendering low doses inductive of strong serum IgG and IgA in the lung

BACKGROUND: H1N1 influenza viruses mutate rapidly, rendering vaccines developed in any given year relatively ineffective in subsequent years. Thus it is necessary to generate new vaccines every year, but this is time-consuming and resource-intensive. Should a highly virulent influenza strain capable...

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Detalles Bibliográficos
Autores principales: Proudfoot, Owen, Esparon, Sandra, Tang, Choon-Kit, Laurie, Karen, Barr, Ian, Pietersz, Geoffrey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350615/
https://www.ncbi.nlm.nih.gov/pubmed/25887952
http://dx.doi.org/10.1186/s12879-015-0838-7