Targeting Mcl-1 for Radiosensitization of Pancreatic Cancers()()

In order to identify targets whose inhibition may enhance the efficacy of chemoradiation in pancreatic cancer, we previously conducted an RNAi library screen of 8,800 genes. We identified Mcl-1 (myeloid cell leukemia-1), an anti-apoptotic member of the Bcl-2 family, as a target for sensitizing pancr...

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Detalles Bibliográficos
Autores principales: Wei, Dongping, Zhang, Qiang, Schreiber, Jason S., Parsels, Leslie A., Abulwerdi, Fardokht A., Kausar, Tasneem, Lawrence, Theodore S., Sun, Yi, Nikolovska-Coleska, Zaneta, Morgan, Meredith A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350640/
https://www.ncbi.nlm.nih.gov/pubmed/25749177
http://dx.doi.org/10.1016/j.tranon.2014.12.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350640/
https://www.ncbi.nlm.nih.gov/pubmed/25749177
http://dx.doi.org/10.1016/j.tranon.2014.12.004

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