Mxi1 and Mxi1-0 Antagonize N-Myc Function and Independently Mediate Apoptosis in Neuroblastoma

Neuroblastoma (NB) is the third most common malignancy of childhood, and outcomes for children with advanced disease remain poor; amplification of the MYCN gene portends a particularly poor prognosis. Mxi1 antagonizes N-Myc by competing for binding to Max and E-boxes. Unlike N-Myc, Mxi1 mediates tra...

Descripción completa

Detalles Bibliográficos
Autores principales: Erichsen, David A., Armstrong, Michael B., Wechsler, Daniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350643/
https://www.ncbi.nlm.nih.gov/pubmed/25749179
http://dx.doi.org/10.1016/j.tranon.2015.01.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350643/
https://www.ncbi.nlm.nih.gov/pubmed/25749179
http://dx.doi.org/10.1016/j.tranon.2015.01.002

Ejemplares similares