Crystal structure of N-{N-[N-acetyl-(S)-leuc­yl]-(S)-leuc­yl}norleucinal (ALLN), an inhibitor of proteasome

The title compound, C(20)H(37)N(3)O(4), also known by the acronym ALLN, is a tripeptidic inhibitor of the proteolytic activity of the proteasomes, enzyme complexes implicated in several neurodegenerative diseases and other disorders, including cancer. The crystal structure of ALLN, solved from synch...

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Detalles Bibliográficos
Autores principales: Czerwinski, Andrzej, Basava, Channa, Dauter, Miroslawa, Dauter, Zbigniew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2015
Materias:
Research Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350719/
https://www.ncbi.nlm.nih.gov/pubmed/25844180
http://dx.doi.org/10.1107/S2056989015002091

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350719/
https://www.ncbi.nlm.nih.gov/pubmed/25844180
http://dx.doi.org/10.1107/S2056989015002091

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