Methionine restriction extends lifespan of Drosophila melanogaster under conditions of low amino acid status

Reduced methionine (Met) intake can extend lifespan of rodents, but whether this regimen represents a general strategy for regulating aging has been controversial. Here we report that Met restriction extends lifespan in both fruit flies and yeast, and that this effect requires low amino acid status....

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Detalles Bibliográficos
Autores principales: Lee, Byung Cheon, Kaya, Alaattin, Ma, Siming, Kim, Gwansu, Gerashchenko, Maxim V., Yim, Sun Hee, Hu, Zhen, Harshman, Lawrence G., Gladyshev, Vadim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350766/
https://www.ncbi.nlm.nih.gov/pubmed/24710037
http://dx.doi.org/10.1038/ncomms4592

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350766/
https://www.ncbi.nlm.nih.gov/pubmed/24710037
http://dx.doi.org/10.1038/ncomms4592

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