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Chronic intermittent hypoxia increases encoding pigment epithelium-derived factor gene expression, although not that of the protein itself, in the temporal cortex of rats,

OBJECTIVE: Obstructive sleep apnea syndrome is mainly characterized by intermittent hypoxia (IH) during sleep, being associated with several complications. Exposure to IH is the most widely used animal model of sleep apnea, short-term IH exposure resulting in cognitive and neuronal impairment. Pigme...

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Detalles Bibliográficos
Autores principales: Julian, Guilherme Silva, de Oliveira, Renato Watanabe, Favaro, Vanessa Manchim, de Oliveira, Maria Gabriela Menezes, Perry, Juliana Cini, Tufik, Sergio, Chagas, Jair Ribeiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350824/
https://www.ncbi.nlm.nih.gov/pubmed/25750673
http://dx.doi.org/10.1590/S1806-37132015000100006