Lung neuroendocrine tumors: correlation of ubiquitinylation and sumoylation with nucleo-cytosolic partitioning of PTEN

BACKGROUND: The tumor suppressor phosphatase and tensin homolog (PTEN) is a pleiotropic enzyme, inhibiting phosphatidyl-inositol-3 kinase (PI3K) signaling in the cytosol and stabilizing the genome in the nucleus. Nucleo-cytosolic partitioning is dependent on the post-translational modifications ubiq...

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Detalles Bibliográficos
Autores principales: Collaud, Stéphane, Tischler, Verena, Atanassoff, Andrej, Wiedl, Thomas, Komminoth, Paul, Oehlschlegel, Christian, Weder, Walter, Soltermann, Alex
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350902/
https://www.ncbi.nlm.nih.gov/pubmed/25884169
http://dx.doi.org/10.1186/s12885-015-1084-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350902/
https://www.ncbi.nlm.nih.gov/pubmed/25884169
http://dx.doi.org/10.1186/s12885-015-1084-5

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