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Quantification of Cellular NEMO Content and Its Impact on NF-κB Activation by Genotoxic Stress

NF-κB essential modulator, NEMO, plays a key role in canonical NF-κB signaling induced by a variety of stimuli, including cytokines and genotoxic agents. To dissect the different biochemical and functional roles of NEMO in NF-κB signaling, various mutant forms of NEMO have been previously analyzed....

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Detalles Bibliográficos
Autores principales: Hwang, Byounghoon, Phan, Funita P., McCool, Kevin, Choi, Eun Young, You, Jinsam, Johnson, Adam, Audhya, Anjon, Miyamoto, Shigeki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350935/
https://www.ncbi.nlm.nih.gov/pubmed/25742655
http://dx.doi.org/10.1371/journal.pone.0116374