Differential requirement of F-actin and microtubule cytoskeleton in cue-induced local protein synthesis in axonal growth cones

BACKGROUND: Local protein synthesis (LPS) via receptor-mediated signaling plays a role in the directional responses of axons to extrinsic cues. An intact cytoskeleton is critical to enact these responses, but it is not known whether the two major cytoskeletal elements, F-actin and microtubules, have...

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Detalles Bibliográficos
Autores principales: Piper, Michael, Lee, Aih Cheun, van Horck, Francisca PG, McNeilly, Heather, Lu, Trina Bo, Harris, William A, Holt, Christine E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350973/
https://www.ncbi.nlm.nih.gov/pubmed/25886013
http://dx.doi.org/10.1186/s13064-015-0031-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350973/
https://www.ncbi.nlm.nih.gov/pubmed/25886013
http://dx.doi.org/10.1186/s13064-015-0031-0

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