Selective inhibitors of nuclear export (SINE) in hematological malignancies

Regulated nucleo-cytoplasmic transport plays a major role in maintaining cellular homeostasis. CRM1 (chromosome region maintenance 1 or exportin 1 or XPO 1) is responsible for the nucleo-cytoplasmic transport of more than 200 proteins, including most of the tumor suppressor proteins (TSP). CRM1 is o...

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Detalles Bibliográficos
Autores principales: Das, Arundhati, Wei, Guoqing, Parikh, Kaushal, Liu, Delong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350974/
https://www.ncbi.nlm.nih.gov/pubmed/25745591
http://dx.doi.org/10.1186/s40164-015-0002-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4350974/
https://www.ncbi.nlm.nih.gov/pubmed/25745591
http://dx.doi.org/10.1186/s40164-015-0002-5

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