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Bora Downregulation Results in Radioresistance by Promoting Repair of Double Strand Breaks
Following DNA double-strand breaks cells activate several DNA-damage response protein kinases, which then trigger histone H2AX phosphorylation and the accumulation of proteins such as MDC1, p53-binding protein 1, and breast cancer gene 1 at the damage site to promote DNA double-strand breaks repair....
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351037/ https://www.ncbi.nlm.nih.gov/pubmed/25742493 http://dx.doi.org/10.1371/journal.pone.0119208 |