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Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans
It is now well established that in yeast, and likely most eukaryotic organisms, initial DNA replication of the leading strand is by DNA polymerase ε and of the lagging strand by DNA polymerase δ. However, the role of Pol δ in replication of the leading strand is uncertain. In this work, we use a rep...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351087/ https://www.ncbi.nlm.nih.gov/pubmed/25742645 http://dx.doi.org/10.1371/journal.pgen.1005049 |