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Replicative DNA Polymerase δ but Not ε Proofreads Errors in Cis and in Trans

It is now well established that in yeast, and likely most eukaryotic organisms, initial DNA replication of the leading strand is by DNA polymerase ε and of the lagging strand by DNA polymerase δ. However, the role of Pol δ in replication of the leading strand is uncertain. In this work, we use a rep...

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Detalles Bibliográficos
Autores principales:	Flood, Carrie L., Rodriguez, Gina P., Bao, Gaobin, Shockley, Arthur H., Kow, Yoke Wah, Crouse, Gray F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351087/ https://www.ncbi.nlm.nih.gov/pubmed/25742645 http://dx.doi.org/10.1371/journal.pgen.1005049

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