Cargando…
Spindle Assembly Checkpoint Acquisition at the Mid-Blastula Transition
The spindle assembly checkpoint (SAC) maintains the fidelity of chromosome segregation during mitosis. Nonpathogenic cells lacking the SAC are typically only found in cleavage stage metazoan embryos, which do not acquire functional checkpoints until the mid-blastula transition (MBT). It is unclear h...
Autores principales: | , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351100/ https://www.ncbi.nlm.nih.gov/pubmed/25741707 http://dx.doi.org/10.1371/journal.pone.0119285 |