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Spindle Assembly Checkpoint Acquisition at the Mid-Blastula Transition

The spindle assembly checkpoint (SAC) maintains the fidelity of chromosome segregation during mitosis. Nonpathogenic cells lacking the SAC are typically only found in cleavage stage metazoan embryos, which do not acquire functional checkpoints until the mid-blastula transition (MBT). It is unclear h...

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Detalles Bibliográficos
Autores principales: Zhang, Maomao, Kothari, Priyanka, Lampson, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351100/
https://www.ncbi.nlm.nih.gov/pubmed/25741707
http://dx.doi.org/10.1371/journal.pone.0119285