Progressive aggregation of alpha-synuclein and selective degeneration of Lewy inclusion-bearing neurons in a mouse model of parkinsonism

Aggregated alpha-synuclein inclusions are found where cell death occurs in several diseases, including Parkinson’s Disease, Dementia with Lewy Bodies and Multiple System Atrophy. However, the relationship between inclusion formation and an individual cell’s fate has been difficult to study with conv...

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Detalles Bibliográficos
Autores principales: Osterberg, Valerie R., Spinelli, Kateri J., Weston, Leah J., Luk, Kelvin C., Woltjer, Randall L., Unni, Vivek K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351119/
https://www.ncbi.nlm.nih.gov/pubmed/25732816
http://dx.doi.org/10.1016/j.celrep.2015.01.060

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351119/
https://www.ncbi.nlm.nih.gov/pubmed/25732816
http://dx.doi.org/10.1016/j.celrep.2015.01.060

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