Dysregulation of X Chromosome Inactivation in High Grade Ovarian Serous Adenocarcinoma

BACKGROUND: One of the two copies of the X chromosome is randomly inactivated in females as a means of dosage compensation. Loss of X chromosome inactivation (XCI) is observed in breast and ovarian cancers, and is frequent in basal-like subtype and BRCA1 mutation-associated breast cancers. We invest...

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Detalles Bibliográficos
Autores principales: Kang, Jun, Lee, Hee Jin, Kim, Jiyoung, Lee, Jae Jun, Maeng, Lee-so
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351149/
https://www.ncbi.nlm.nih.gov/pubmed/25742136
http://dx.doi.org/10.1371/journal.pone.0118927

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351149/
https://www.ncbi.nlm.nih.gov/pubmed/25742136
http://dx.doi.org/10.1371/journal.pone.0118927

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