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Dysregulation of X Chromosome Inactivation in High Grade Ovarian Serous Adenocarcinoma
BACKGROUND: One of the two copies of the X chromosome is randomly inactivated in females as a means of dosage compensation. Loss of X chromosome inactivation (XCI) is observed in breast and ovarian cancers, and is frequent in basal-like subtype and BRCA1 mutation-associated breast cancers. We invest...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351149/ https://www.ncbi.nlm.nih.gov/pubmed/25742136 http://dx.doi.org/10.1371/journal.pone.0118927 |