Tracking replication enzymology in vivo by genome-wide mapping of ribonucleotide incorporation

Ribonucleotides are frequently incorporated into DNA during eukaryotic replication. Here we map the genome-wide distribution of these ribonucleotides as markers of replication enzymology in budding yeast, using a new 5′-DNA end-mapping method, Hydrolytic End Sequencing. HydEn-Seq of DNA from ribonuc...

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Detalles Bibliográficos
Autores principales: Clausen, Anders R., Lujan, Scott A., Burkholder, Adam B., Orebaugh, Clinton D., Williams, Jessica S., Clausen, Maryam F., Malc, Ewa P., Mieczkowski, Piotr A., Fargo, David C., Smith, Duncan J., Kunkel, Thomas A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351163/
https://www.ncbi.nlm.nih.gov/pubmed/25622295
http://dx.doi.org/10.1038/nsmb.2957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351163/
https://www.ncbi.nlm.nih.gov/pubmed/25622295
http://dx.doi.org/10.1038/nsmb.2957

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