DBC1 Functions as a Tumor Suppressor by Regulating p53 Stability

DBC1 (deleted in breast cancer 1), also known as CCAR2 or KIAA1967 is an important negative regulator of SIRT1 and cellular stress response. Although the Dbc1 gene localizes at a region that is homozygously deleted in breast cancer, its role in tumorigenesis remains unclear. It has been suggested to...

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Detalles Bibliográficos
Autores principales: Qin, Bo, Minter-Dykhouse, Katherine, Yu, Jia, Zhang, Jun, Liu, Tongzheng, Zhang, Haoxing, Lee, Seung Baek, Kim, Jung Jin, Wang, Liewei, Lou, Zhenkun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351187/
https://www.ncbi.nlm.nih.gov/pubmed/25732823
http://dx.doi.org/10.1016/j.celrep.2015.01.066

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351187/
https://www.ncbi.nlm.nih.gov/pubmed/25732823
http://dx.doi.org/10.1016/j.celrep.2015.01.066

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