Aberrant Liver Insulin Receptor Isoform A Expression Normalises with Remission of Type 2 Diabetes after Gastric Bypass Surgery

Type 2 diabetes mellitus (T2DM) results from a combination of progressive insulin resistance and loss of pancreatic beta cell function and/or mass. Insulin signalling occurs through the insulin receptor, (INSR) which is alternatively spliced into two isoforms: INSRA (-exon 11) and INSRB (+exon 11)....

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Detalles Bibliográficos
Autores principales: Besic, Vinko, Shi, Hongjun, Stubbs, Richard S., Hayes, Mark T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351188/
https://www.ncbi.nlm.nih.gov/pubmed/25742416
http://dx.doi.org/10.1371/journal.pone.0119270

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351188/
https://www.ncbi.nlm.nih.gov/pubmed/25742416
http://dx.doi.org/10.1371/journal.pone.0119270

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