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Subgingival Microbial Communities in Leukocyte Adhesion Deficiency and Their Relationship with Local Immunopathology

Leukocyte Adhesion Deficiency I (LAD-I) is a primary immunodeficiency caused by single gene mutations in the CD18 subunit of β2 integrins which result in defective transmigration of neutrophils into the tissues. Affected patients suffer from recurrent life threatening infections and severe oral dise...

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Detalles Bibliográficos
Autores principales: Moutsopoulos, Niki M., Chalmers, Natalia I., Barb, Jennifer J., Abusleme, Loreto, Greenwell-Wild, Teresa, Dutzan, Nicolas, Paster, Bruce J., Munson, Peter J., Fine, Daniel H., Uzel, Gulbu, Holland, Steven M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351202/
https://www.ncbi.nlm.nih.gov/pubmed/25741691
http://dx.doi.org/10.1371/journal.ppat.1004698