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Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting

The capacity of Plasmodium falciparum parasitized erythrocytes (pRBC) to adhere to the endothelial lining in the microvasculature and to red blood cells (RBC) is associated with the virulence of the parasite, the pathogenesis and development of severe malaria. Rosetting, the binding of uninfected RB...

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Detalles Bibliográficos
Autores principales: Angeletti, Davide, Sandalova, Tatyana, Wahlgren, Mats, Achour, Adnane
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351205/
https://www.ncbi.nlm.nih.gov/pubmed/25742651
http://dx.doi.org/10.1371/journal.pone.0118898