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Binding of Subdomains 1/2 of PfEMP1-DBL1α to Heparan Sulfate or Heparin Mediates Plasmodium falciparum Rosetting

The capacity of Plasmodium falciparum parasitized erythrocytes (pRBC) to adhere to the endothelial lining in the microvasculature and to red blood cells (RBC) is associated with the virulence of the parasite, the pathogenesis and development of severe malaria. Rosetting, the binding of uninfected RB...

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Détails bibliographiques
Auteurs principaux: Angeletti, Davide, Sandalova, Tatyana, Wahlgren, Mats, Achour, Adnane
Format: Online Article Texte
Langue:English
Publié: Public Library of Science 2015
Sujets:
Accès en ligne:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351205/
https://www.ncbi.nlm.nih.gov/pubmed/25742651
http://dx.doi.org/10.1371/journal.pone.0118898