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The role of mitochondrial DNA mutation on neurodegenerative diseases

Many researchers have reported that oxidative damage to mitochondrial DNA (mtDNA) is increased in several age-related disorders. Damage to mitochondrial constituents and mtDNA can generate additional mitochondrial dysfunction that may result in greater reactive oxygen species production, triggering...

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Detalles Bibliográficos
Autores principales: Cha, Moon-Yong, Kim, Dong Kyu, Mook-Jung, Inhee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351410/
https://www.ncbi.nlm.nih.gov/pubmed/25766619
http://dx.doi.org/10.1038/emm.2014.122