Cargando…

The role of mitochondrial DNA mutation on neurodegenerative diseases

Many researchers have reported that oxidative damage to mitochondrial DNA (mtDNA) is increased in several age-related disorders. Damage to mitochondrial constituents and mtDNA can generate additional mitochondrial dysfunction that may result in greater reactive oxygen species production, triggering...

Descripción completa

Detalles Bibliográficos
Autores principales:	Cha, Moon-Yong, Kim, Dong Kyu, Mook-Jung, Inhee
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351410/ https://www.ncbi.nlm.nih.gov/pubmed/25766619 http://dx.doi.org/10.1038/emm.2014.122

Ejemplares similares

The role of cell type-specific mitochondrial dysfunction in the pathogenesis of Alzheimer’s disease
por: Kim, Dong Kyu, et al.
Publicado: (2019)

Special issue on neurodegenerative diseases and their therapeutic approaches
por: Kim, Jungsu, et al.
Publicado: (2015)

Mimicry of Central-Peripheral Immunity in Alzheimer's Disease and Discovery of Neurodegenerative Roles in Neutrophil
por: Park, Joseph, et al.
Publicado: (2019)

Mitochondrial DNA Repair in Neurodegenerative Diseases and Ageing
por: Bazzani, Veronica, et al.
Publicado: (2022)

Mitochondria-Specific Accumulation of Amyloid β Induces Mitochondrial Dysfunction Leading to Apoptotic Cell Death
por: Cha, Moon-Yong, et al.
Publicado: (2012)

Diverse Molecular Targets for Therapeutic Strategies in Alzheimer's Disease
por: Han, Sun-Ho, et al.
Publicado: (2014)

The Role of Mitochondrial DNA Mutations in Cardiovascular Diseases
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Protein‐Induced Pluripotent Stem Cells Ameliorate Cognitive Dysfunction and Reduce Aβ Deposition in a Mouse Model of Alzheimer's Disease
por: Cha, Moon‐Yong, et al.
Publicado: (2016)

Deep proteome profiling of the hippocampus in the 5XFAD mouse model reveals biological process alterations and a novel biomarker of Alzheimer’s disease
por: Kim, Dong Kyu, et al.
Publicado: (2019)

Visualization of Altered Hippocampal Connectivity in an Animal Model of Alzheimer’s Disease
por: Jeon, Seong Gak, et al.
Publicado: (2018)

Nurr1 (NR4A2) regulates Alzheimer’s disease‐related pathogenesis and cognitive function in the 5XFAD mouse model
por: Moon, Minho, et al.
Publicado: (2018)

Abnormalities of Mitochondrial Dynamics in Neurodegenerative Diseases
por: Gao, Ju, et al.
Publicado: (2017)

Characterization of mutations in PRNP (prion) gene and their possible roles in neurodegenerative diseases
por: Bagyinszky, Eva, et al.
Publicado: (2018)

Promise and Pitfalls of Mitochondrial Replacement for Prevention and Cure of Heritable Neurodegenerative Diseases Caused by Deleterious Mutations in Mitochondrial DNA
por: Paine, Ananta, et al.
Publicado: (2016)

Roles of sigma-1 receptors on mitochondrial functions relevant to neurodegenerative diseases
por: Weng, Tzu-Yu, et al.
Publicado: (2017)

Role of Mitochondrial Protein Import in Age-Related Neurodegenerative and Cardiovascular Diseases
por: Bogorodskiy, Andrey, et al.
Publicado: (2021)

Mitochondrial Dynamics in Neurodegenerative Diseases: Unraveling the Role of Fusion and Fission Processes
por: Grel, Hubert, et al.
Publicado: (2023)

The Functional Roles and Applications of Immunoglobulins in Neurodegenerative Disease
por: Sim, Kyu-Young, et al.
Publicado: (2020)

Mitochondrial calcium signalling and neurodegenerative diseases
por: Britti, Elena, et al.
Publicado: (2018)

Unlocking the Complexity of Mitochondrial DNA: A Key to Understanding Neurodegenerative Disease Caused by Injury
por: Singh, Larry N., et al.
Publicado: (2021)

Mitochondrial Dysfunction and Neurodegenerative Disorders: Role of Nutritional Supplementation
por: Mantle, David, et al.
Publicado: (2022)

Oxidative Toxicity in Neurodegenerative Diseases: Role of Mitochondrial Dysfunction and Therapeutic Strategies
por: Facecchia, Katie, et al.
Publicado: (2011)

Mitochondrial and Cell Death Mechanisms in Neurodegenerative Diseases
por: Martin, Lee J.
Publicado: (2010)

Dysfunctional Mitochondrial Dynamics in the Pathophysiology of Neurodegenerative Diseases
por: Haun, Florian, et al.
Publicado: (2013)

Riboflavin Responsive Mitochondrial Dysfunction in Neurodegenerative Diseases
por: Udhayabanu, Tamilarasan, et al.
Publicado: (2017)

Mitochondrial MicroRNAs in Aging and Neurodegenerative Diseases
por: John, Albin, et al.
Publicado: (2020)

Significance of mitochondrial activity in neurogenesis and neurodegenerative diseases
por: Ozgen, Serra, et al.
Publicado: (2021)

Mitochondrial Bioenergy in Neurodegenerative Disease: Huntington and Parkinson
por: Tassone, Annalisa, et al.
Publicado: (2023)

The Role of Mitochondrial DNA Mutations in Mammalian Aging
por: Kujoth, Gregory C, et al.
Publicado: (2007)

Mitochondrial dysfunctions in neurodegenerative diseases: role in disease pathogenesis, strategies for analysis and therapeutic prospects
por: Rey, Federica, et al.
Publicado: (2021)

Thrombospondin-1 protects against Aβ-induced mitochondrial fragmentation and dysfunction in hippocampal cells
por: Kang, Seokjo, et al.
Publicado: (2018)

The role of mitochondrial DNA mutations and free radicals in disease and ageing
por: Lagouge, M, et al.
Publicado: (2013)

Contributions of Microglia to Structural Synaptic Plasticity
por: Kim, Kyung Ho, et al.
Publicado: (2013)

Mitochondrial DNA mutations in disease and aging
por: Park, Chan Bae, et al.
Publicado: (2011)

Peripheral inflammatory biomarkers in Alzheimer’s disease: a brief review
por: Park, Jong-Chan, et al.
Publicado: (2020)

Disruption of blood-brain barrier in Alzheimer disease pathogenesis
por: Kook, Sun-Young, et al.
Publicado: (2013)

Dysfunction of Mitochondrial Ca(2+) Regulatory Machineries in Brain Aging and Neurodegenerative Diseases
por: Jung, Hyunsu, et al.
Publicado: (2020)

The Function of the Mitochondrial Calcium Uniporter in Neurodegenerative Disorders
por: Liao, Yajin, et al.
Publicado: (2017)

The Role of Microglia in the Development of Neurodegenerative Diseases
por: Lee, Jae-Won, et al.
Publicado: (2021)

Mitochondrial Dynamics in Cancer and Neurodegenerative and Neuroinflammatory Diseases
por: Corrado, Mauro, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_robfeasro11craras981iq0f47