Association of nicotinamide-N-methyltransferase mRNA expression in human adipose tissue and the plasma concentration of its product, 1-methylnicotinamide, with insulin resistance

AIMS/HYPOTHESIS: Nicotinamide-N-methyltransferase (NNMT) was recently shown to be upregulated in mouse models of insulin resistance and obesity. So far, it is unknown whether NNMT is regulated in human disease. We have explored the hypothesis that white adipose tissue (WAT) NNMT expression and plasm...

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Detalles Bibliográficos
Autores principales: Kannt, Aimo, Pfenninger, Anja, Teichert, Lenore, Tönjes, Anke, Dietrich, Arne, Schön, Michael R., Klöting, Nora, Blüher, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351435/
https://www.ncbi.nlm.nih.gov/pubmed/25596852
http://dx.doi.org/10.1007/s00125-014-3490-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351435/
https://www.ncbi.nlm.nih.gov/pubmed/25596852
http://dx.doi.org/10.1007/s00125-014-3490-7

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