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Targeted Gene Delivery to the Enteric Nervous System Using AAV: A Comparison Across Serotypes and Capsid Mutants

Recombinant adeno-associated virus (AAV) vectors are one of the most widely used gene transfer systems in research and clinical trials. AAV can transduce a wide range of biological tissues, however to date, there has been no investigation on targeted AAV transduction of the enteric nervous system (E...

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Detalles Bibliográficos
Autores principales: Benskey, Matthew J, Kuhn, Nathan C, Galligan, James J, Garcia, Joanna, Boye, Shannon E, Hauswirth, William W, Mueller, Christian, Boye, Sanford L, Manfredsson, Fredric P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351472/
https://www.ncbi.nlm.nih.gov/pubmed/25592336
http://dx.doi.org/10.1038/mt.2015.7