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Targeted Gene Delivery to the Enteric Nervous System Using AAV: A Comparison Across Serotypes and Capsid Mutants
Recombinant adeno-associated virus (AAV) vectors are one of the most widely used gene transfer systems in research and clinical trials. AAV can transduce a wide range of biological tissues, however to date, there has been no investigation on targeted AAV transduction of the enteric nervous system (E...
Autores principales: | Benskey, Matthew J, Kuhn, Nathan C, Galligan, James J, Garcia, Joanna, Boye, Shannon E, Hauswirth, William W, Mueller, Christian, Boye, Sanford L, Manfredsson, Fredric P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351472/ https://www.ncbi.nlm.nih.gov/pubmed/25592336 http://dx.doi.org/10.1038/mt.2015.7 |
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