Mutagenic effects induced by the attack of NO(2) radical to the guanine-cytosine base pair

We investigate the attack of the nitrogen dioxide radical (NO(•)(2)) to the guanine—cytosine (GC) base pair and the subsequent tautomeric reactions able to induce mutations, by means of density functional theory (DFT) calculations. The conducted simulations allow us to identify the most reactive sit...

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Detalles Bibliográficos
Autores principales: Cerón-Carrasco, José P., Requena, Alberto, Zúñiga, José, Jacquemin, Denis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351615/
https://www.ncbi.nlm.nih.gov/pubmed/25798437
http://dx.doi.org/10.3389/fchem.2015.00013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351615/
https://www.ncbi.nlm.nih.gov/pubmed/25798437
http://dx.doi.org/10.3389/fchem.2015.00013

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