Cargando…
Mutagenic effects induced by the attack of NO(2) radical to the guanine-cytosine base pair
We investigate the attack of the nitrogen dioxide radical (NO(•)(2)) to the guanine—cytosine (GC) base pair and the subsequent tautomeric reactions able to induce mutations, by means of density functional theory (DFT) calculations. The conducted simulations allow us to identify the most reactive sit...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351615/ https://www.ncbi.nlm.nih.gov/pubmed/25798437 http://dx.doi.org/10.3389/fchem.2015.00013 |