Ferrets exclusively synthesize Neu5Ac and express naturally humanized influenza A virus receptors

Mammals express the sialic acids N-acetylneuraminic acid (Neu5Ac) and N-glycolylneuraminic acid (Neu5Gc) on cell surfaces, where they act as receptors for pathogens, including influenza A virus (IAV). Neu5Gc is synthesized from Neu5Ac by the enzyme cytidine monophosphate-N-acetylneuraminic acid hydr...

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Detalles Bibliográficos
Autores principales: Ng, Preston S.K., Böhm, Raphael, Hartley-Tassell, Lauren E., Steen, Jason A., Wang, Hui, Lukowski, Samuel W., Hawthorne, Paula L., Trezise, Ann E.O., Coloe, Peter J., Grimmond, Sean M., Haselhorst, Thomas, von Itzstein, Mark, Paton, Adrienne W., Paton, James C., Jennings, Michael P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351649/
https://www.ncbi.nlm.nih.gov/pubmed/25517696
http://dx.doi.org/10.1038/ncomms6750

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351649/
https://www.ncbi.nlm.nih.gov/pubmed/25517696
http://dx.doi.org/10.1038/ncomms6750

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