Formononetin inhibits enterovirus 71 replication by regulating COX- 2/PGE(2) expression

BACKGROUND: The activation of ERK, p38 and JNK signal cascade in host cells has been demonstrated to up-regulate of enterovirus 71 (EV71)-induced cyclooxygenase-2 (COX-2)/ prostaglandins E(2) (PGE(2)) expression which is essential for viral replication. So, we want to know whether a compound can inh...

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Detalles Bibliográficos
Autores principales: Wang, Huiqiang, Zhang, Dajun, Ge, Miao, Li, Zhuorong, Jiang, Jiandong, Li, Yuhuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351682/
https://www.ncbi.nlm.nih.gov/pubmed/25890183
http://dx.doi.org/10.1186/s12985-015-0264-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351682/
https://www.ncbi.nlm.nih.gov/pubmed/25890183
http://dx.doi.org/10.1186/s12985-015-0264-x

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