A hidden Markov approach for ascertaining cSNP genotypes from RNA sequence data in the presence of allelic imbalance by exploiting linkage disequilibrium

BACKGROUND: Allelic specific expression (ASE) increases our understanding of the genetic control of gene expression and its links to phenotypic variation. ASE testing is implemented through binomial or beta-binomial tests of sequence read counts of alternative alleles at a cSNP of interest in hetero...

Descripción completa

Detalles Bibliográficos
Autores principales: Steibel, Juan P, Wang, Heng, Zhong, Ping-Shou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351697/
https://www.ncbi.nlm.nih.gov/pubmed/25887316
http://dx.doi.org/10.1186/s12859-015-0479-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351697/
https://www.ncbi.nlm.nih.gov/pubmed/25887316
http://dx.doi.org/10.1186/s12859-015-0479-2

Ejemplares similares