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Improving the computational efficiency of fully Bayes inference and assessing the effect of misspecification of hyperparameters in whole-genome prediction models

BACKGROUND: The reliability of whole-genome prediction models (WGP) based on using high-density single nucleotide polymorphism (SNP) panels critically depends on proper specification of key hyperparameters. A currently popular WGP model labeled BayesB specifies a hyperparameter π, that is `loosely u...

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Detalles Bibliográficos
Autores principales: Yang, Wenzhao, Chen, Chunyu, Tempelman, Robert J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351701/
https://www.ncbi.nlm.nih.gov/pubmed/25885894
http://dx.doi.org/10.1186/s12711-015-0092-x