FAAH genetic variation enhances fronto-amygdala function in mouse and human

Cross-species studies enable rapid translational discovery and produce the broadest impact when both mechanism and phenotype are consistent across organisms. We developed a knock-in mouse that biologically recapitulates a common human mutation in the gene for fatty acid amide hydrolase (FAAH) (C385A...

Descripción completa

Detalles Bibliográficos
Autores principales: Dincheva, Iva, Drysdale, Andrew T., Hartley, Catherine A., Johnson, David C., Jing, Deqiang, King, Elizabeth C., Ra, Stephen, Gray, Megan, Yang, Ruirong, DeGruccio, Ann Marie, Huang, Chienchun, Cravatt, Benjamin F., Glatt, Charles E., Hill, Matthew N., Casey, B. J., Lee, Francis S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351757/
https://www.ncbi.nlm.nih.gov/pubmed/25731744
http://dx.doi.org/10.1038/ncomms7395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351757/
https://www.ncbi.nlm.nih.gov/pubmed/25731744
http://dx.doi.org/10.1038/ncomms7395

Ejemplares similares