Transport domain unlocking sets the uptake rate of an aspartate transporter

Glutamate transporters terminate neurotransmission by clearing synaptically released glutamate from the extracellular space, allowing repeated rounds of signaling and preventing glutamate-mediated excitotoxicity. Crystallographic studies on an archaeal homologue, Glt(Ph), showed that distinct transp...

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Detalles Bibliográficos
Autores principales: Akyuz, Nurunisa, Georgieva, Elka R., Zhou, Zhou, Stolzenberg, Sebastian, Cuendet, Michel A., Khelashvili, George, Altman, Roger B., Terry, Daniel S., Freed, Jack H., Weinstein, Harel, Boudker, Olga, Blanchard, Scott C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351760/
https://www.ncbi.nlm.nih.gov/pubmed/25652997
http://dx.doi.org/10.1038/nature14158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351760/
https://www.ncbi.nlm.nih.gov/pubmed/25652997
http://dx.doi.org/10.1038/nature14158

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