The Emperor's New Clothes: PDE5 and the Heart

Phosphodiesterase-5 (PDE5) is highly expressed in the pulmonary vasculature, but its expression in the myocardium is controversial. Cyclic guanosine monophosphate (cGMP) activates protein kinase G (PKG), which has been hypothesized to blunt cardiac hypertrophy and negative remodeling in heart failur...

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Detalles Bibliográficos
Autores principales: Degen, Chantal V., Bishu, Kalkidan, Zakeri, Rosita, Ogut, Ozgur, Redfield, Margaret M., Brozovich, Frank V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351884/
https://www.ncbi.nlm.nih.gov/pubmed/25747598
http://dx.doi.org/10.1371/journal.pone.0118664

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351884/
https://www.ncbi.nlm.nih.gov/pubmed/25747598
http://dx.doi.org/10.1371/journal.pone.0118664

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