Cargando…

The Emperor's New Clothes: PDE5 and the Heart

Phosphodiesterase-5 (PDE5) is highly expressed in the pulmonary vasculature, but its expression in the myocardium is controversial. Cyclic guanosine monophosphate (cGMP) activates protein kinase G (PKG), which has been hypothesized to blunt cardiac hypertrophy and negative remodeling in heart failur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Degen, Chantal V., Bishu, Kalkidan, Zakeri, Rosita, Ogut, Ozgur, Redfield, Margaret M., Brozovich, Frank V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351884/ https://www.ncbi.nlm.nih.gov/pubmed/25747598 http://dx.doi.org/10.1371/journal.pone.0118664

Ejemplares similares

Anti-Remodeling Effects of Rapamycin in Experimental Heart Failure: Dose Response and Interaction with Angiotensin Receptor Blockade
por: Bishu, Kalkidan, et al.
Publicado: (2013)

The Emperor’s New Clothes
por: Cunningham, WF
Publicado: (2000)

THE EMPEROR's CLOTHES
por: Morley, David
Publicado: (2003)

Precision public health—the Emperor’s new clothes
por: Taylor-Robinson, David, et al.
Publicado: (2019)

About stagnation and the emperor’s new clothes
por: Crombez, Geert
Publicado: (2015)

Burnout in healthcare – the Emperor’s New Clothes
por: Marlicz, Wojciech, et al.
Publicado: (2023)

The potential role of MLC phosphatase and MAPK signalling in the pathogenesis of vascular dysfunction in heart failure
por: Ogut, Ozgur, et al.
Publicado: (2008)

Osteoporosis: the emperor has no clothes
por: Järvinen, T L N, et al.
Publicado: (2015)

Visual snow syndrome and the emperor’s new clothes
por: Kondziella, Daniel
Publicado: (2022)

Dyspnea and Mechanical Ventilation: The Emperor Has No Clothes
por: Schwartzstein, Richard M., et al.
Publicado: (2022)

The National Service Framework for Coronary Heart Disease: The Emperor’s New Clothes
por: Hampton, John R
Publicado: (2000)

The emperor's new clothes: hypersensitivity of the new cardiac isoenzymes
por: Han, Ma Ai Thanda, et al.
Publicado: (2013)

The Berlin definition: real change or the emperor's new clothes?
por: Phillips, Charles R
Publicado: (2013)

Consequences of Misunderstanding Pain - And Another View of The Emperor's New Clothes
por: Barbuto, John
Publicado: (2009)

The Emperor Has No Clothes? Searching for Dysregulation in Sepsis
por: Alcock, Joe
Publicado: (2018)

The emperor's new clothes: investment strategies that help keep you covered
por: Glassman, Saly A
Publicado: (2012)

The Emperor's New Clothes: a Critical Appraisal of Evidence-based Medicine
por: Tebala, Giovanni D.
Publicado: (2018)

The Emperor’s New Clothes—An Epistemological Critique of Traditional Chinese Veterinary Acupuncture
por: Magalhães-Sant’Ana, Manuel
Publicado: (2019)

Unpicking the Emperor’s New Clothes: Perceived Attributes of the Captain in Sports Teams
por: Fransen, Katrien, et al.
Publicado: (2019)

The emperor has no clothes: OAB can be cured surgically
por: Petros, Peter
Publicado: (2022)

Centralized nociplastic pain causing fibromyalgia: an emperor with no cloths?
por: Martínez-Lavín, Manuel
Publicado: (2022)

Differential phosphorylation of LZ+/LZ- MYPT1 isoforms by PKGIα: implication for vascular reactivity
por: Yuen, Samantha, et al.
Publicado: (2011)

MYPT1 Protein Isoforms Are Differentially Phosphorylated by Protein Kinase G
por: Yuen, Samantha, et al.
Publicado: (2011)

Keep calm and carry on: moral panic, predatory publishers, peer review, and the emperor's new clothes
por: Houghton, Frank
Publicado: (2022)

Con: Renal denervation for all resistant hypertensive patients: the Emperor's new clothes
por: Persu, Alexandre, et al.
Publicado: (2014)

The randomised clinical trial and the hazard ratio – medical research’s Emperor’s New Clothes?
por: Stephens, Richard, et al.
Publicado: (2014)

Health-related quality of life after critical care—the emperor’s new clothes
por: Sjöberg, Folke, et al.
Publicado: (2020)

Pulmonary vasodilator therapy as treatment for patients with a Fontan circulation: the Emperor’s new clothes?
por: Ridderbos, Floris-Jan S., et al.
Publicado: (2018)

Meta‐audit of laboratory ISO accreditation inspections: measuring the old emperor's clothes
por: Wilson, Ian G., et al.
Publicado: (2015)

Where Does Evidence from New Trials for Schizophrenia Fit with the Existing Evidence: A Case of the Emperor's New Clothes?
por: Jayaram, Mahesh, et al.
Publicado: (2012)

Bridging Exercise Science, Cognitive Psychology, and Medical Practice: Is “Cognitive Fatigue” a Remake of “The Emperor’s New Clothes”?
por: Pattyn, Nathalie, et al.
Publicado: (2018)

The emperor's new shibboleth
por: Petsko, Gregory A
Publicado: (2004)

The only emperor is the emperor of ice-cream
por: Potter, Polyxeni
Publicado: (2011)

Response to “Trials for depressive disorder in adolescents: the emperor's new clothes,” a letter to the editor by Alain Braillon, MD, PhD
por: Butcher, Nancy J., et al.
Publicado: (2020)

Are SGLT-2 Inhibitors the Future of Heart Failure Treatment? The EMPEROR-Preserved and EMPEROR-Reduced Trials
por: Williams, David M., et al.
Publicado: (2020)

Clothing the Emperor: Dynamic Root–Shoot Allocation Trajectories in Relation to Whole-Plant Growth Rate and in Response to Temperature
por: Robinson, David, et al.
Publicado: (2019)

Does the FDA have regulatory authority over adult autologous stem cell therapies? 21 CFR 1271 and the emperor's new clothes
por: Freeman, Michael, et al.
Publicado: (2012)

Palestine 100 years ago, Hans Christian Anderson’s tale of ‘The Emperor’s New Clothes’, malaria elimination and today’s failure of engagement with the community
por: Alexander, Anton
Publicado: (2022)

Questioning on consistency of a Stagnation Scale in Medication Overuse Headache: one more added to a plea of emperor’s clothes?
por: Innamorati, Marco, et al.
Publicado: (2015)

The emperor has no clothes: a synthesis of findings from the Transformative Research on the Alcohol industry, Policy and Science research programme
por: McCambridge, Jim, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_1kj72aiig3570v63v8td20lpcl