Small-molecule inhibitor of Bcl-2 (TW-37) suppresses growth and enhances cisplatin-induced apoptosis in ovarian cancer cells

BACKGROUND: Bcl-2 plays a major role in the pathobiology and drug resistance of ovarian cancer, and inhibition of bcl-2 was useful for OC therapy. It has previously reported that TW-37, a small-molecule inhibitor of Bcl-2 family proteins, inhibited cell growth and induced apoptosis in many cancer ce...

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Detalles Bibliográficos
Autores principales: Wang, Haixia, Zhang, Zhifeng, Wei, Xiuping, Dai, Ruizhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351907/
https://www.ncbi.nlm.nih.gov/pubmed/25823945
http://dx.doi.org/10.1186/s13048-015-0130-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4351907/
https://www.ncbi.nlm.nih.gov/pubmed/25823945
http://dx.doi.org/10.1186/s13048-015-0130-x

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